| CITY | BRAND | ADDRESS | RAILROAD | TELEPHONE | RATING |
| Charleston | Howard Johnson | 3640 Dorchester Road | CSX / Norfolk Southern | 843.554.4140 | T-B-2 |
| Clemson | Holiday Inn | 894 Tiger Boulevard | Norfolk Southern | ||
| Sleep Inn | 1303 Tiger Boulevard | Norfolk Southern | |||
| Clinton | West Side Motor Inn | 303 West Carolina | CSX | ||
| Columbia | AmeriSuites | 7525 Two Notch Road | CSX | ||
| Columbia | Comfort Inn | 7700 Two Notch Road | CSX | ||
| Columbia | Embassy Suites Hotel | 200 Stoneridge Drive | CSX | 803-252-8700 | T-B-x |
| Columbia | Fairground Plaza Hotel | 621 South Assembly Street | CSX / Norfolk Southern | ||
| Columbia | Holiday Inn Coliseum | 630 South Assembly Street | CSX / Norfolk Southern | ||
| Columbia | Holiday Inn Northeast | 7510 Two Notch Road | CSX | ||
| Columbia | Ramada Plaza | 8105 Two Notch Road | CSX | ||
| Columbia | Red Roof Inn | 7580 Two Notch Road | CSX | ||
| Columbia | Travelodge & Suites | 1539 Horseshoe Drive | CSX | ||
| Columbia | Wingate Inn | 8300 Two Notch Road | CSX | ||
| Estill | Palmetto Inn | Cynthias Lane | CSX | ||
| Florence | Best Western Inn | 1808 West Lucas Street | South Carolina Central | ||
| Florence | Country Inn & Suites | 1739 Manderville Road | South Carolina Central | ||
| Florence | Hampton Inn - North | 1826 West Lucas Street | South Carolina Central | ||
| Florence | Ramada Inn | 2038 West Lucas Street | South Carolina Central | ||
| Goose Creek | Econo Lodge | 401 Goose Creek Boulevard N | CSX | 843-797-8200 | T-B-2 |
| Goose Creek | Quality Inn | 103 Redbank Road | CSX | 843-572-9500 | x-x-x |
| Greenville | Econo Lodge | 719 Bypass 25 Northeast | CSX | ||
| Jonesville | Stardust Motel | 1041 Jonesville Highway | Norfolk Southern | ||
| Laurens | Travel Inn | 621 Harper Street | CSX | ||
| Ridgeway | Ridgeway Motel | Highway 34 West | Norfolk Southern | ||
| Seneca | Budget Motel | 1003 North 1st Street | Norfolk Southern | ||
| Winnsboro | Plantation Inn | US 321 | Norfolk Southern | ||
| Yemassee | Super 8 | 21 Castle Hall Road | CSX | ||
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